Welcome to the new MedCram lecture, we will discuss New coronavirus updates 75,200 confirmed cases today, Based on data from WHO and China’s CDC 2000 total deaths. Total recovery was 14,772. Take a look at Worldometer Divided into active and inactive cases. 16,814, inactive cases Of these 88 % have recovered or been discharged and 12 % have died. Of course, these numbers There may be an underestimation, As mentioned earlier. It is impossible to count every patient with new coronary pneumonia Statisticians believe the number of confirmed cases is underestimated. Possible causes include Mild patients choose not to seek medical treatment and their detection capabilities are limited Shortage of resources, missed reports during data collection, etc. Most are mild cases If we divide the cases into The situation inside and outside mainland China Outside China. Here is another chart where you can see. Trends Seems more new cases. Every day Cases appear to be declining in mainland China. The total number of deaths exceeds 2,000 Mention here. Efforts by the laboratory to combat the new crown virus. Covid-19 NPR has a nice article about antibodies. The first point is how antibodies are produced. These B cells in your body, each have different receptors B cells have only one task to make antibodies.

These cellular receptors receive any type of Antigens you may be exposed to Antigens may be viral or bacterial proteins. There are many different types of millions of receptors on B cells in your body. Almost any foreign material Can stimulate the corresponding B cells. See here, Every B cell has a different antigen receptor Binds to only one specific antigen. So if a virus invades The virus will stimulate its specific B cells, it will activate Getting cytokines help from T cells causing that cell Clones that quickly divide and expand into a population of B cells. You have thousands of these B cells, These B cells produce antibodies, which go to attack, Virus-containing cells or the virus itself. After the operation is completed, these B cells will disappear on their own, but a small part will always be left B cells if the virus strikes again prepare to attack again. This is how the virus usually works. So If you get an antiviral vaccine like polio or Hepatitis B virus, the vaccine goes the same way: Stimulate: B cells.

When getting vaccinated, Sometimes only the viral protein is vaccinated, not the virus itself, So you do not really get sick and cause B. Cells Produces a lot of antibodies and if an infection occurs, The body is always ready to respond. Sometimes the virus mutates and the protein structure, Large variations can also occur and previous antibodies will fail. This is how a cold happens Colds multiple times a year because of different viruses, Rhinovirus vs, ordinary coronavirus or maybe Rhinovirus mutates. So much that you were previously immune Fighting viruses is no longer effective Topic back This time. They are discussing drugs that can prevent the virus, But there are related companies doing similar things They find patients who are recovering from infection extract antibodies from them, Because the patients immune system is already able to clear the virus Screen millions of different immune cells to Find one Can cure new crown virus

Another frontier job, they brought experimental mice, Let mice use human immune cells To produce complete human antibodies, which is very incredible. So the next step is to inject the new crown virus into these mice. Take out these antibodies and see if they work Run a test and look at the antibody New Coronavirus Is SARS CoV-2 effective? This is a new treatment that may come. We saw them in the USA Today report When reviewing the data from China. Again, They claim that the new crown virus is 20 times more lethal than the flu. This statement is based on the case, the fatality rate

It was said that the death toll had exceeded 2,000. We can see here. The global death toll from the virus was 2009 (. As of Tuesday night). The total infection is more than 75,000. If so, Calculating total mortality. The virus is 2.3 %, But the seasonal influenza case, the fatality rate in the U.S., is about 0.1 %, So this is more fatal than the flu, but not as good as SARS in 2002 About 10 %. Nonetheless, many experts believe that it is too early to estimate mortality. Many people are now willing to divide the total deaths by the number of diagnoses. The estimated fatality rate could be very different from the real figure. Another unfortunate news is another doctor who died in China. Dr

Liu is the president of a hospital in Wuhan China, A neurosurgeon in a new crown virus endemic area. These B cells become plasma cells, Immunoglobulin antibody, And how the virus infects human cells, which are more specific. We will discuss these issues in detail later Recently. Many people have asked about the prognosis of this disease. We have seen some Cases recovering in the United States Is a patient in Washington, But now there are some questions. Rumors Claimed that people could be infected with the virus twice. The second reaction will be much more serious and may not have an adequate immune response. I haven’t seen any similar reports so now It is too early to answer this question. One thing worth mentioning: That is, the general situation After a person is infected with a virus. Their ability to withstand secondary bacterial infections diminishes so Secondary bacterial infections, after viral infections, are not uncommon. I want to end this update with a particularly good article, An article published on February 12, 2020 Practical advice on intensive care and anesthesia medicine On how to deal with patients with new crown virus.

I will be Below is a link to post this article published in Canada. Looking back at the 2002 SARS virus experience, it talks about some very practical experiences: E.g intensive care unit. What protective equipment is needed? Air flow, (, positive or negative airflow) in these rooms. For example, if you are Positive pressure ventilation in the operating room, you definitely do not want Surgical patients carry the virus, to the article mention switching these patients to negative pressure Surgery in the room to prevent cross infection. I think this is an excellent read, for doctors Can take better care of patients with new CoVid-19 coronavirus, Also discussed when to use N95 masks, and this Electric air purifying respirators are also called PAPRS. Who needs to wear these Also discussed the concept of hot, warm and cold zones? The hot zone is the room where the patient is Negative. Pressure, ventilation is required.

The warm area is when you are not in the patient’s room Still in the intensive care unit And the cold zone is when you are not in the intensive care unit. I think this is Valuable information Place. A link below Thanks for listening